Karen M Vasquez Selected Research

triplex DNA (H-DNA)

1/2019	A tunable assay for modulators of genome-destabilizing DNA structures.
1/2018	Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.
1/2017	Alternative DNA structure formation in the mutagenic human c-MYC promoter.
12/2013	DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells.
8/2010	Human DHX9 helicase unwinds triple-helical DNA structures.
9/2004	Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.

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Karen M Vasquez Research Topics

Disease

35	Neoplasms (Cancer) 01/2022 - 09/2003
10	Genomic Instability 01/2020 - 06/2008
5	Inflammation (Inflammations) 01/2019 - 07/2008
4	Carcinogenesis 09/2020 - 01/2005
3	Breast Neoplasms (Breast Cancer) 03/2021 - 04/2006
3	Xeroderma Pigmentosum (Kaposi's Disease) 09/2003 - 04/2002
2	Lung Neoplasms (Lung Cancer) 01/2021 - 11/2015
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 01/2009
2	Leukemia 01/2018 - 02/2006
2	Gallbladder Neoplasms (Gallbladder Cancer) 01/2017 - 04/2007
2	Fanconi Anemia (Fanconi's Anemia) 03/2013 - 07/2010
1	Virus Diseases (Viral Diseases) 07/2021
1	Triple Negative Breast Neoplasms 03/2021
1	Obesity 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 09/2020
1	Adenocarcinoma of Lung 03/2020
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Esophageal Neoplasms (Esophageal Cancer) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2019
1	Pancreatic Neoplasms (Pancreatic Cancer) 11/2018
1	Chromosomal Instability (Chromosome Stability) 01/2017
1	Osteosarcoma (Osteogenic Sarcoma) 03/2011
1	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2008
1	Decompression Sickness (Bends) 07/2008
1	Rheumatoid Arthritis 07/2008
1	Sepsis (Septicemia) 07/2008
1	Carcinoma (Carcinomatosis) 04/2007
1	Lymphoma (Lymphomas) 02/2006
1	Chromosome Breakage 02/2006
1	Turcot syndrome 06/2005
1	Plasmacytoma 09/2004
1	Burkitt Lymphoma (Burkitt's Lymphoma) 09/2004

Drug/Important Bio-Agent (IBA)

17	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2003
13	Proteins (Proteins, Gene)FDA Link 03/2021 - 04/2002
9	B-Form DNA (B-DNA)IBA 01/2020 - 01/2009
6	Long Noncoding RNAIBA 03/2021 - 11/2015
6	Biomarkers (Surrogate Marker)IBA 09/2020 - 11/2015
6	triplex DNA (H-DNA)IBA 01/2019 - 09/2004
5	Z-Form DNA (Z-DNA)IBA 01/2022 - 02/2006
4	HMGB1 Protein (HMG1)IBA 11/2019 - 07/2008
4	ChromatinIBA 01/2019 - 07/2008
3	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2019
3	Ficusin (Psoralen)IBA 07/2009 - 06/2005
2	HMGB ProteinsIBA 01/2020 - 01/2019
2	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 09/2008
2	A-Form DNA (A-DNA)IBA 01/2017 - 04/2002
2	OligonucleotidesIBA 09/2014 - 04/2006
2	Gemcitabine FDA Link 09/2014 - 04/2006
2	EnzymesIBA 03/2014 - 03/2013
1	Interferon Type IIBA 07/2021
1	Progesterone Receptors (Progesterone Receptor)IBA 03/2021
1	Estrogens (Estrogen)FDA Link 03/2021
1	beta CateninIBA 01/2021
1	Cadherins (E-Cadherin)IBA 01/2021
1	Untranslated RNA (Noncoding RNA)IBA 09/2020
1	Cyclin D1IBA 03/2020
1	VimentinIBA 03/2020
1	CateninsIBA 03/2020
1	LuciferasesIBA 03/2020
1	Molecular Probes (Molecular Probe)IBA 12/2019
1	PlatinumIBA 01/2019
1	Small Nucleolar RNA (snoRNA)IBA 01/2019
1	ProteomeIBA 01/2019
1	HMGB3 ProteinIBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019
1	SphingosineIBA 11/2018
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2018
1	Phosphates (Orthophosphate)IBA 11/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2018
1	5' Untranslated Regions (5' UTR)IBA 01/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2017
1	AntimetabolitesIBA 09/2014
1	Single-Stranded DNA (DNA, Single Stranded)IBA 03/2014
1	NucleotidesIBA 01/2013
1	GuanineIBA 01/2013
1	2-chloroethyl methyl sulfideIBA 03/2010
1	Mustard Gas (Sulfur Mustard)IBA 03/2010
1	2,6-dithiopurineIBA 03/2010
1	CarcinogensIBA 03/2010
1	2-chloroethyl ethyl sulfideIBA 03/2010
1	NitrogenIBA 09/2008
1	Biological ProductsIBA 07/2008
1	TOR Serine-Threonine KinasesIBA 04/2007
1	Therapeutic UsesIBA 04/2007
1	MacrolidesIBA 04/2007
1	Sirolimus (Rapamycin)FDA Link 04/2007
1	NucleosidesIBA 04/2006
1	purineIBA 02/2006
1	pyrimidineIBA 02/2006
1	Replication Protein AIBA 09/2003
1	Staphylococcal Protein A (Protein A)IBA 09/2003
1	Protein CIBA 09/2003

Therapy/Procedure

6	Therapeutics 09/2020 - 07/2008
5	Drug Therapy (Chemotherapy) 01/2019 - 04/2006
1	Radiotherapy 01/2019
1	Immunotherapy 11/2018